Jortani Clinical Trials Laboratory

About 

Epigenetics and biomarkers of environmentally induced cancers, post-operative personalized pain management as well as use of AI and “Big Data” in laboratory diagnostics.  Detection and measurement of drugs, therapeutics and poisons, herbal medicine poisonings, and the use of pharmacogenetics in postmortem investigations.

Key Research Areas

  • Post-operative pain management
  • Epigenetics of environmentally related cancer risk
  • Pharmacogenetics in postmortem toxicology investigations
  • Biomarkers of Alzheimer’s disease
  • Use of AI and big data in personalized pain management

Current Projects

  • Biomarker Discovery Through Proteomics and Genomics Research Program
  • Novel Biomarker Discovery using the latest technologies.

Recent Publications

  • Langman LJ, Gaskins J, Korte E, Maluf C, Wooderchak-Donahue WL, McMillin GA, Jannetto PJ, Hartley B, Malkani A, Yakkanti M, Jortani SA. Endogenous and iatrogenic sources of variability in response to opioid therapy in Post-Surgical and injured orthopedic patients. Clinica Chimica Acta. 2021;522:105-113.
  • Whitt AG, Karimi V, Gaskins JT, Atkins R, Roach A, Hartley B, Malkani A, Yakkanti M, Jortani SA. Psychotropic inhibitors of CYP2D6 prolong use of hydrocodone for pain management. Drug Metabolism and Precision Medicine.  https://doi.org/10.1515/dmpt-2024-0031.
  • Alghamdi N, Robinson T, Sharp C, Jortani SA. Interpretation of Discordant Results in Maternal/Newborn Dyad Drug Screening, American Journal of Pediatrics. Volume 8, Issue 4, December 2022, pp. 244-251. doi: 10.11648/j.ajp.20220804.19

Team 

  • Jennifer Pittman, MT
  • Nicole Pozzi, MT
  • Kristie Rappe, MT

Jortani Clinical Trials Laboratory

School of Medicine/Pathology & Laboratory Medicine

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Location

Medical Dental Research Building, 217 and 228