Kenneth Palmer Lab
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About
Translational research focusing on prevention and treatment of infectious diseases and cancer. Dr. Palmer employs human-relevant models and human clinical studies to evaluate new prophylactic and therapeutic methods. He is particularly interested in developing products with broad-spectrum antiviral activity. Dr. Palmer also directs the Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, which has state-of-the-art facilities that support testing of new diagnostics and vaccines and therapeutics to prevent and treat emerging infectious disease threats.
Key Research Areas
- Discovery and development of broad-spectrum antivirals.
- Targeting oligomannose glycans for prevention and treatment of infections.
- Delivery of antivirals to mucosal surfaces for prevention of viral infection.
- Infections in the upper respiratory tract.
- Impact of environmental toxicants on respiratory infections.
- Sexually transmitted viral infections.
- Human papillomavirus-associated cancers.
Current Projects
- Targeting antiviral lectin Griffithsin to the upper respiratory tract to prevent viral infections.
- Mucosal immune responses to emerging pathogens.
- Impact of environmental pollution exposure on respiratory infections.
Team
- Amanda B. Lasnik, Laboratory Manager, Amanda.lasnik@louisville.edu
- Dr. Maryam Zahin, Program Manager in charge of clinical and regulatory affairs. Maryam.zahin@louisville.edu
- Megan Bezold, MD-PhD student. Megan.bezold@louisville.edu
Recent Publications
- NMDA receptor antagonists mitigate COVID-19-induced neuroinflammation and improve survival in a mouse model
- Mucosal and Serum Neutralization Immune Responses Elicited by COVID-19 mRNA Vaccination in Vaccinated and Breakthrough-Infection Individuals: A Longitudinal Study from Louisville Cohort
- Impact of chronic ethanol consumption and SARS‐COV‐2 on the liver and intestine: A pilot dose–response study in mice
- CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection
Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin